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A study comparing two anesthesia gases desflurane and sevoflurane to evaluate awakening and recovery after keyhole gallbladder surgery under general anesthesia

Comparison of Desflurane and Sevoflurane for Emergence and Recovery Characteristics in Adult Patients Undergoing Laparoscopic Cholecystectomy Under General Anesthesia: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113956
Enrollment
140
Registered
2026-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: Desflurane: Group A participants will be given Desflurane inhalational anesthesia to maintain an adequate depth of anesthesia BIS 40 to 60 administered throughout the surgery as

Sponsors

Regional Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists ASA grade I and II scheduled for elective Lap cholecystectomy and is willing to participate in the study and has signed the informed consent form

Exclusion criteria

Exclusion criteria: Patient refusal , Pregnancy or lactation, history of malignant hyperthermia, severe cardio pulmonary disease, endocrine or renal disorders, obesity, neurological conditions and patients who have a history of severe allergic reactions to inhalational agents or other components of anesthesia

Design outcomes

Primary

MeasureTime frame
To compare the time to emergence from Anesthesia between Desflurane and SevofluraneTimepoint: Time from cessation of anesthesia to patient first sign of consciousness starting from baseline to every 5 minutes post extubation till 30 minutes

Secondary

MeasureTime frame
To evaluate hemodynamic stability during induction maintenance & emergency phases of anesthesiaTimepoint: Blood pressure pulse & oxygen saturation will be measured from baseline to first 1 hour in a 5 minute interval

Countries

India

Contacts

Public ContactDr Y ARUNKUMAR SINGH

Regional Institute of Medical Sciences

yaks48@yahoo.com9862282518

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026