A Study of Nausea and Vomiting After Surgery: Two Different Methods of Giving Paracetamol and Tramadol

A Randomised Trial to Compare an Infusion of Paracetamol with Tramadol versus Sequential Administration of Paracetamol and Tramadol for Postoperative Nausea and Vomiting PONV in Patients Undergoing Surgery under Spinal Anaesthesia - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/07/113936

Enrollment

144

Registered

2026-07-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N359- Urethral stricture, unspecified Health Condition 2: M160- Bilateral primary osteoarthritis of hip Health Condition 3: N400- Benign prostatic hyperplasia without lower urinary tract symptoms Health Condition 4: M662- Spontaneous rupture of extensor tendons

Interventions

Intervention1: Paracetamol + Tramadol infusion: Intravenous infusion of Paracetamol 1 g combined with Tramadol 25 mg administered 15 minutes before completion of surgery under spinal anaesthesia. Cont

Eligibility

Inclusion criteria

Inclusion criteria: Elective infraumbilical surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Hepatic impairment Renal impairment Chronic opioid/analgesic use Hypersensitivity to study drugs

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomitingTimepoint: After 1hr,2hr,4hr,8hr,12hr,24hr	—

Secondary

Measure	Time frame
Incidence of shivering Dose of rescue antiemetic Total analgesic consumption in 24 hoursTimepoint: After 1hr,2hr,4hr,8hr,12hr,24hr	—

Countries

India

Contacts

Public ContactANUP MARKI

Rajendra Institute of Medical Sciences, Ranchi

ekramrims@yahoo.co.in8210696628

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026