Health Condition 1: R570- Cardiogenic shock
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients more than equal to 18 years Diagnosed with cardiogenic shock Planned for intra-aortic balloon pump insertion as part of routine clinical care Adequate transtemporal acoustic window for MCA insonation
Exclusion criteria
Exclusion criteria: Intracranial hemorrhage or large territorial stroke Known severe carotid artery stenosis Known intracranial pathology affecting cerebral blood flow Inadequate acoustic window for TCD Patients in whom T1 measurement cannot be safely performed due to hemodynamic instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in middle cerebral artery End Diastolic Velocity measured by Transcranial Doppler following initiation of IABP supportTimepoint: 1 Immediately before IABP insertion 2 60 minutes after initiation of IABP support | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in PSV MFV PI and RI following IABP initiation assessment of waveform characteristics including diastolic augmentation and reversal patterns correlation of changes in cerebral blood flow parameters with systemic hemodynamic variables vasopressor requirements, left ventricular function and IABP support characteristicsTimepoint: 1 Immediately before IABP insertion 2 60 minutes after initiation of IABP support | — |
Countries
India
Contacts
Medanta The Medicity Gurgaon