A Clinical Study to Assess the Effect of an Ayurvedic Cleansing Therapy Virechana on Stroke Recovery

Effect of Virechana Karma on Brain Derived Neurotrophic Factor BDNF and Clinical Outcomes in Ischemic Stroke Pakshaghata An Open Label Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/07/113919

Enrollment

100

Registered

2026-07-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I639- Cerebral infarction, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients in the age group of 30 to 70 years. 2. Patients having a first attack of stroke within a period of one year. 3. Conscious patient. 4. Patients indicated for Virechana Karma. 5. Patient willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients in the age group of 30 to 70 years. 2. Patients having a first attack of stroke within a period of one year. 3. Conscious patient. 4. Patients indicated for Virechana Karma. 5. Patient willing to participate in the study. 1. Marked mental impairment. 2. Patients having bed sores. 3. Age below 30 years and above 70 years. 4. Pregnant women and lactating mothers. 5. Patients who have lost bowel and bladder control. 6. Comatose and unconscious patients. 7. Uncontrolled Diabetes mellitus, hypertension or any other systemic illness. 8. Intracranial infections such as meningitis. 9. Space occupying lesions of brain such as tumour. 10. Post traumatic paralysis patients. 11. Congenital defects-diffuse sclerosis, cerebral agenesis etc. and other major illness. 12. Patients contraindicated for Virechana Karma.

Design outcomes

Primary

Measure	Time frame
It is expected that the intervention will increase BDNF levels in the patients of ischaemic stroke. Timepoint: In both groups, at 1st at baseline. 2nd In group A, after completion of Virechana Karma i.e. may take 13 to 23 days. In group B, on 15th day.	—

Secondary

Measure	Time frame
The intervention is expected to reduce stroke severity & improve quality of life of patients.Timepoint: At baseline, In group A, after completion of Virechana Karma i.e. may take 13 to 23 days. In group B, on 15th day.	—

Countries

India

Contacts

Public ContactProf Dr Anup Thakar

Institute of Teaching and Research in Ayurveda

anup_thakar@yahoo.com9427776660

Outcome results