A study comparing different solutions used to clean abdomen during surgery in patients with perforation peritonitis.

COMPARISON OF PATIENT OUTCOMES AFTER USING NORMAL SALINE, METRONIDAZOLE, AND GENTAMICIN FOR PERITONEAL LAVAGE IN PATIENTS OF PERFORATION PERITONITIS. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/07/113870

Enrollment

222

Registered

2026-07-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis

Interventions

Intervention1: Metronidazole as peritoneal lavage in patients of perforation peritonitis.: In this arm patients with perforation peritonitis will be given peritoneal lavage using 200ml metronidazole.

Eligibility

Inclusion criteria

Inclusion criteria: All patients with an age group of 18 to 60 years diagnosed with perforation peritonitis

Exclusion criteria

Exclusion criteria: Peritonitis secondary to trauma Peritonitis secondary to gynaecological intervention Peritonitis secondary to malignancy Known history of allergy to antibiotics in the study

Design outcomes

Primary

Measure	Time frame
To compare the post-operative outcomes in three groups in terms of - 1. Surgical site infection 2. Burst abdomen 3. Intra-abdominal abscess 4. Average length of hospital stay.Timepoint: Following operation of the patient, all the three groups i.e. peritoneal lavage with normal saline, metronidazole and gentamicin will be observed on day 3,7,15 and 30 for surgical site infection, burst abdomen, intra-abdominal abscess and average length of hospital stay.	—

Measure

Time frame

To compare the post-operative outcomes in three groups in terms of - 1. Surgical site infection 2. Burst abdomen 3. Intra-abdominal abscess 4. Average length of hospital stay.Timepoint: Following operation of the patient, all the three groups i.e. peritoneal lavage with normal saline, metronidazole and gentamicin will be observed on day 3,7,15 and 30 for surgical site infection, burst abdomen, intra-abdominal abscess and average length of hospital stay.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDR SHASHANK CHAUDHRY

DR BABA SAHEB AMBEDKAR MEDICAL COLLEGE AND HOSPITAL

shashank_chaudhry@yahoo.co.in9818276244

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026