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Does combining plasma-rich growth factors with bioactive glass, a bone graft material, improve clinical and radiographic healing compared with bioactive glass alone in patients with bone defects caused by gum disease?

Clinical Evaluation of PRGF Combined with Bioactive glass (BG) compared to Bioactive glass alone in Periodontal Intra-Bony Defects: A Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113850
Enrollment
30
Registered
2026-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: PRGF COMBINED WITH BIOACTIVE GLASS: PLASMA RICH IN GROWTH FACTORS COMBINED WITH BIOACTIVE GLASS placed into the intrabony defect and evaluated at baseline, 3,6 and 9 months Control Inte

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with stage 3 grade B Periodontitis with pesence of periodntal 3 walled intrabony defects.

Exclusion criteria

Exclusion criteria: patients who underwent surgery in the past 6 months, systemically compromised patients who interfere with healing, and those who are unwilling to participate were excluded

Design outcomes

Primary

MeasureTime frame
PPD RAL BONEFILLTimepoint: BASELINE 3MONTHS 6MONTHS 9MONTHS—

Secondary

MeasureTime frame
GMLCHANGE GI PITimepoint: BASELINE 3MONTHS 6MONTHS 9MONTHS—

Countries

India

Contacts

Public ContactDr Sai sree Lanka

institute of dental sciences

rinkeemohanty@soa.ac.in9848707761

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026