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Comparison of Hyaluronic Acid Gel and Laser Therapy Along with Deep Cleaning for the Treatment of Gum Disease

Comparative Evaluation of the Clinical Efficacy of Conventional Curettage with Subgingival Hyaluronic Acid Gel Application Versus Laser-Assisted New Attachment Procedure LANAP as Adjuncts to Scaling and Root Instrumentation in Stage II Periodontitis: A Double blind, Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113812
Enrollment
148
Registered
2026-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: SRI and Conventional Curettage and subgingival HA Gel: 0.2 persent Hyaluronic acid gel will be applied only once during the treatment. Then patient will be followed up at 3 months and 6

Sponsors

Sudipa Garai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed with Stage II Periodontitis Patients present with probing pocket depth of greater than and equal to 4mm

Exclusion criteria

Exclusion criteria: Patients with uncontrolled systemic diseases History of allergy to hyaluronic acid or any other drugs used in the study Antibiotic or periodontal therapy in past 6 months Smokers having more than 10 cigarettes per day Pregnant or lactating women Uncooperative patients

Design outcomes

Primary

MeasureTime frame
Clinical Attachment LevelTimepoint: Baseline, 3 months, 6 months—

Secondary

MeasureTime frame
Probing Pocket DepthTimepoint: Baseline, 3 months, 6 months;Gingival Bleeding IndexTimepoint: Baseline, 3 months, 6 months;Full Mouth Plaque IndexTimepoint: Baseline, 3 months, 6 months;Patient-Reported OutcomeTimepoint: 1 day,3 days,5 days, 7 days—

Countries

India

Contacts

Public ContactAbhaya Chandra Das

Institute of dental sciences Bhubaneswar

abhayadas@soa.ac.in9437088379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026