Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
Intervention1: Propofol group: Propofol will be administered as an initial intravenous dose of 20 mg followed by additional doses based on the patients American Society of Anaesthesiologists classific
Sponsors
AIIMS, Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged more or equal to 18 years scheduled for flexible bronchoscopy Indicated for diagnostic procedures such as brushing washings bronchoalveolar lavage or endobronchial or transbronchial biopsy Ability & willingness to provide written informed consent
Exclusion criteria
Exclusion criteria: Age less than 18 years Renal or hepatic insufficiency Seizure disorder or psychiatric illness Hemodynamic instability including ding cardiac failure hypovolemia heart rate less than 50 beats per min or second or third degree heart block Known or suspected allergy to midazolam fentanyl or propofol Pregnancy or Lactation Patient unwilling or unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the composite procedural comfort scores among the two sedation regimens. Timepoint: Assessed during flexible bronchoscopy and recorded at the end of the procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time measured using the Modified Observer Assessment of Alertness Sedation score. Timepoint: Immediately after completion of bronchoscopy until achievement of a Modified Observer Assessment of Alertness Sedation score of 5.;Patient reported discomfort and procedure related cough severity measured using a 10 cm visual analogue scale. Timepoint: After recovery immediately after achievement of a Modified Observer Assessment of Alertness Sedation score of 5 and before discharge. | — |
Countries
India
Contacts
Public ContactDr Alkesh Kumar Khurana
AIIMS, Bhopal
Outcome results
None listed