Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Mechanical Power Guided Ventilation: Mechanical power will be assessed after initiation of mechanical ventilation and will be recorded at hourly intervals throughout the intra operative
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged 18 years and above, of either sex, belonging to American Society of Anesthesiologists (ASA) physical status I II, scheduled to undergo elective major abdominal surgery (anticipated duration more than 2 hours) under general anaesthesia will be enrolled.
Exclusion criteria
Exclusion criteria: 1. Patients refusal to participate in the study 2. Patients undergoing emergency laparotomy 3. Known COPD or other chronic lung diseases 4. Patients undergoing oesophageal surgery 5. Known deformity of chest wall or thoracic spine 6. Pre-existing significant cardiac, renal and hepatic diseases 7. Intraoperative massive blood loss (defined by blood loss more than 40 ml/kg) or massive transfusion (more than 8 unit of PRBC transfusion during surgery) 8. Patients with history of previous thoracic surgery. 9. BMI more than 30 kg per metre square, and less than 18 kg per metre square
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative pulmonary complications as per Melbourne Group Scale Score 2 Postoperative pulmonary complications will be defined as positive when patients presented with four or more of the eight dichotomous factors. Timepoint: Will be assessed Preoperatively for baseline and on Postoperative day three and seven. The primary Outcome will be assessed on Postoperative Day seven | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-operative pulmonary complications as per Melbourne Group Scale Score 2Timepoint: Preoperatively for Baseline & on postoperative Day 3 & 7;PPCs as per European Perioperative Clinical Outcome, EPCO, definitions at day 7. Postoperative pulmonary complications include any postoperative occurrence of respiratory infection, respiratory failure - Hypoxemia or need for oxygen/ventilatory support, pleural effusion, atelectasis, pneumothorax, bronchospasm, or aspiration pneumonitis.Timepoint: Preoperatively for Baseline & on postoperative Day 3 & 7;Duration of hospital stayTimepoint: From the day of Surgey until the day of Hospital discharge- in number of days.;Lung ultrasound score at post-extubation at the Post-Anesthesia Care Unit: 12 lung areas bilaterally.Timepoint: On Postoperative day Zero immediately after extubation in Post anaesthesia care unit. | — |
Countries
India
Contacts
Public ContactDr Dalim Kumar Baidya
AIIMS New Delhi
Outcome results
None listed