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A study to compare different treatments for stopping tooth decay from getting worse in children

Comparative Efficacy of Silver Diamine Fluoride with KI, Nano silver fluoride and Sodium fluoride varnish in arresting the progression of dental caries in children: A Randomized clinical trial. - SDF-KINaF Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113714
Enrollment
102
Registered
2026-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Silver Diamine fluoride with KI, Nano Silver Fluoride and Sodium fluoride: Silver Diamine Fluoride (SDF) is a topical medicament used for arresting dental caries due to its antibacteria

Sponsors

Dr Sagili Lahari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy Children aged 6-12 years with active dentinal caries in primary molars Absence of pulp involvement Participants without any systemic diseases

Exclusion criteria

Exclusion criteria: Any signs of pain, swelling, abscess, fistula primary teeth with irreversible pulpitis Tooth close to exfoliation Children with any hypersensitivity to Iodine

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the reduction of dental caries using Silver Diamine Fluoride with potassium iodide, Nano silver fluoride, and sodium fluoride varnish by assessing changes in caries activity, lesion size, depth, colour, presence of pain, progression of caries, and any adverse effects at baseline, 3 months, 6 months and 12 months.Timepoint: 0 days,3 months,6 months,9 months and 12 months

Secondary

MeasureTime frame
Secondary outcomes include changes in caries activity, lesion size, depth, & colour, presence or absence of pain, progression or failure of caries at baseline, 3 months, 6 months & 12 months & any adverse effects during the study period.Timepoint: baseline, 3 months, 6 months, 9 months & 12 months

Countries

India

Contacts

Public ContactSagili Lahari

Narayana Dental Collage and Hospital

nimskrishna2007@gmail.com9440206976

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026