Health Condition 1: Z991- Dependence on respirator
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Institute of Critical Care Medicine and Anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: 1 Resolution or improvement of the condition requiring MV 2 Adequate oxygenation demonstrated by arterial oxygen saturation greater than 90 percent with an inspired oxygen fraction of 0.5 or less or a ratio of arterial oxygen partial pressure to FiO2 PaO2/FiO2 of at least 150 mmHg both with positive end-expiratory pressure or PEEP at or below 8 cmH2O 3 Absence of significant respiratory acidosis 4 Stable hemodynamic condition with systolic blood pressure between 90 and 160 mmHg without or with minimal inotropic support and heart rate below 120 beats per minute 5 Adequate level of consciousness without sedation 6 No excessive tracheobronchial secretions 7 Presence of an effective cough reflex
Exclusion criteria
Exclusion criteria: 1 Age less than 18 years 2 Pregnancy 3 Presence of thoracostomy pneumothorax or pneumomediastinum 4 Presence of flail chest or rib fractures 5 Pre existing cervical spinal injury history or diagnosis of neuromuscular disorders 6 History of diaphragm paralysis 7 The quality of the diaphragmatic ultrasonography images is poor and cannot be used for analysis 8 The patients next of kin refuses participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of VVI compared to D RSBI in predicting weaning outcomesTimepoint: Sustained spontaneous breathing for less than equal to 48 hours post extubation without reintubation or need for non invasive ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Effectiveness of VVI alone in predicting weaning success 2 Associations between VVI and/or D-RSBI values and key clinical endpoints ventilator free days at 28 days ICU length of stay hospital length of stay and 28 day mortality Timepoint: 1 Ventilator free days at 28 days 2 ICU length of stay 3 Hospital length of stay 4 28 day mortality | — |
Countries
India
Contacts
Public ContactDr Deepak Govil
Medanta The Medicity Gurgaon
Outcome results
None listed