Health Condition 1: I708- Atherosclerosis of other arteries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Indian adults aged 18 years or older Individuals undergoing CT coronary angiography and carotid Doppler ultrasonography on the same day as part of the study protocol Willing and able to provide written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: Individuals younger than 18 years Individuals who are unwilling or unable to provide written informed consent. Individuals with a known history of allergy or hypersensitivity to iodinated contrast media Individuals with incomplete or poor-quality CT coronary angiography or carotid Doppler ultrasound images that are unsuitable for analysis Individuals with a history of carotid artery surgery or carotid artery stenting that may interfere with carotid artery assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 To assess the relationship between carotid IMT on Doppler ultrasound and CAD severity on CT coronary angiography 2 To characterize plaque and utilize radionics for plaque analysis based on CT coronary angiography imagesTimepoint: Baseline or day 0 All study imaging including CT coronary angiography and carotid Doppler ultrasonography will be performed on the same day Outcome measures will be derived from these baseline images, with offline radiomic and AI-based image analysis performed subsequently | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate radiomics-based ML models in differentiating significant, intermediate and non-significant CADTimepoint: baseline | — |
Countries
India
Contacts
kasturba medical college and hospital manipal MAHE