Health Condition 1: K746- Other and unspecified cirrhosis ofliver
Conditions
Interventions
Intervention1: Combined Aerobic and Resistance Exercise (CARE) Programme: Structured home-based integrated exercise training programme consisting of aerobic exercise and progressive resistance trainin
Sponsors
Krishna Vishwa Vidyapeeth (Deemed to be University), Karad
Eligibility
Inclusion criteria
Inclusion criteria: Male and female participants aged 30 50 years. Diagnosed cases of decompensated liver cirrhosis. Child-Pugh score between 7 and 15. Presence of sarcopenia as determined by study assessment criteria. Willingness to participate and provide written informed consent.
Exclusion criteria
Exclusion criteria: Coexisting cardiac conditions. Coronary artery disease. Cardiac arrhythmias. Dialysis-dependent chronic renal insufficiency. Any condition preventing safe participation in exercise training. Unwillingness to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Functional Capacity measured by Six-Minute Walk Test (6MWT) distance (meters),Change in Skeletal Muscle Mass measured by Bioelectrical Impedance Analysis (BIA) (kg)Timepoint: Baseline and 12 weeks post-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in Serum Glutamic-Oxaloacetic Transaminase (SGOT/AST) levels (U/L)Timepoint: Baseline and 12 weeks post-intervention;Change in Serum Glutamic-Pyruvic Transaminase (SGPT/ALT) levels (U/L)Timepoint: Baseline and 12 weeks post-intervention | — |
Countries
India
Contacts
Public ContactRushikesh Patil
krishna institute of medical science karad
Outcome results
None listed