Health Condition 1: F90-F98- Behavioral and emotional disorders with onset usually occurring in childhood and adolescence
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Dr Puneet Khanna
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients aged between 8-17 years 2) Scheduled for elective non-cardiac surgery under general anaesthesia 3) Parents or legal guardians of pediatric patients who provide written informed consent will be eligible for inclusion.
Exclusion criteria
Exclusion criteria: 1) History suggestive of dementia (either listed in the medical record or reported by the patient) or any neurological disorder 2) History of any cerebral surgeries (including neurosurgeries, head and neck surgeries) 3) History suggestive of psychiatric disease like schizophrenia, dementia, anxiety or other disorder affecting cognition, mental dysfunction 4) Prescription of central nervous system active medication (eg: antidepressants, antipsychotics, sedatives)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study expects to document a clinically significant prevalence of PMTS symptoms at 1-month post-surgery (T2), anticipated based on historical surgical cohort data. By 3-months post-surgery (T3), it is hypothesized that a statistically significant proportion of children will show spontaneous symptom resolution. However, a persistent subset of the cohort is expected to exhibit chronic, unresolving PMTS trajectories, with severe functional impairment across academic, social, and family domains. Timepoint: 1) Pre-operative Baseline(T0) 2) 24hrs Post-operative (T1) 3) 1 Month follow up (T2) 4) 3 Months follow up (T3) | — |
Secondary
| Measure | Time frame |
|---|---|
| Several intraoperative and postoperative clinical factors are expected to emerge as independent predictors of chronic PMTS. Specifically, prolonged surgical duration, unexpected post-operative complications, high discharge pain scores , and prolonged hospital stays are hypothesized to significantly multiply the odds of a persistent distress trajectory, even when controlling for baseline coping characteristics. Consistent with bioecological models of health, pediatric patients from lower socioeconomic backgrounds and those whose parents report elevated baseline anxiety are expected to show significantly higher rates of chronic distress and lower perceived support over time, highlighting a key target group for post-operative clinical outreach.Timepoint: 1) Pre-operative Baseline(T0) 2) 24hrs Post-operative (T1) 3) 1 Month follow up (T2) 4) 3 Months follow up (T3) | — |
Countries
India
Contacts
Public ContactDr Puneet Khanna
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed