Health Condition 1: Q20-Q28- Congenital malformations of the circulatory system
Conditions
Interventions
Intervention1: Aminoacid: Aminoacid (10 percent) intravenous infusion at the rate of 1.5g/kg/day from induction of anesthesia, continued
intraoperatively and postoperatively till enteral intake resume
Sponsors
Postgraduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Pediatric patients aged 29 days to 6 years scheduled for elective cardiac surgery with cardiopulmonary bypass
Exclusion criteria
Exclusion criteria: Neonates less than or equal to 28 days of life, Cardiac surgery without cardiopulmonary bypass, Inborn errors of metabolism, Hypersensitivity to Aminoacid, Severe hepatic insufficiency (ALT/AST 2 times above normal range), Severe renal insufficiency (creatinine 2 times above normal range), Preoperative mechanical ventilation or inotropes, Emergency surgery, Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU-free daysTimepoint: 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| acute kidney injury, need for RRTTimepoint: 48 hours, ICU discharge;ICU length of stayTimepoint: ICU discharge;Duration of invasive mechanical ventilationTimepoint: ICU discharge;hospital length of stayTimepoint: hospital discharge;mortality (ICU, hospital)Timepoint: 28 days, 90 days;ICU acquired infectionsTimepoint: ICU discharge | — |
Countries
India
Contacts
Public ContactRajarajan Ganesan
PostGraduate Institute of Medical Education and Research
Outcome results
None listed