Health Condition 1: M255- Pain in joint
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Meril Life Sciences Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: 1 Participant of age 18 and above, irrespective of gender presenting with orthopedic conditions such as osteoarthritis, tendon injuries, cartilage defects, fractures, spinal fusion requirements, sports-related injuries, chronic wound or soft tissue healing 2 Participants considered failure of conservative treatment measures oral medications, physical therapy, and/or injection therapy 3 Participants who are able, and willing to provide voluntary, written informed consent to participate in this study 4 Participants showing Kellgren-Lawrence classification Grade 0-3
Exclusion criteria
Exclusion criteria: 1 Participants who are unwilling or unable to sign the Informed Consent Document 2 Participants who have following conditions Platelet Dysfunction Syndrome, Critical Thrombocytopaenia, Hypofibrinogenaemia, Hemodynamic Instability, Auto-Immune Diseases, Malignancy, Sepsis, Acute Chronic Infection, Chronic Liver Pathology, Anti coagulation Therapy ASA Therapy, Newborns 3 Pregnant or breast-feeding women 4 Participants showing Kellgren-Lawrence classification Grade 4 5 Participants who are using NSAIDs for chronic pain management 6 Participants undergoing physiotherapy prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 To Assess the Pain Severity Using Visual Analog Scale and Adverse events and Improvement in Range of Motion and Improvement in Knee Society Scores Timepoint: baseline, Intra-operative, Through Discharge, 2 weeks, 30 days, 3 months, 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Post-treatment Participant s Satisfaction 2 International Knee Documentation Committee Score 3 Reduced Use of Analgesics 4 The 6-Minute Pain-Free Walking Distance 5 Kellgren Lawrence Classification 6 Hematological Assessment 7 Procedure Time 8 Platelets, Activation, White cells System Classification 9 DEPA Classification 10 SF-36 Questionnaire Quality of lifeTimepoint: 1 2 weeks, 30 days, 3 months, 6 months 2 Baseline, 30 days 3 2 weeks, 30 days, 3 months, 6 months 4 Baseline, 2 weeks, 30 days, 3 months, 6 months 5 Baseline, 2 weeks, 30 days, 3 months, 6 months 6 Baseline, 2 weeks, 30 days, 3 months, 6 months 7 Intraoperative 8 Intraoperative 9 Intraoperative 10 Baseline, 2 weeks, 30 days, 3 months, 6 months | — |
Countries
India
Contacts
Public ContactDr Kirankumar Shetty
Meril Life Sciences Pvt Ltd
Outcome results
None listed