Health Condition 1: J960- Acute respiratory failure
Conditions
Interventions
Intervention1: Enhanced INSURE(ENSURE): Lung ultrasound score more than 8 will be a criterion for surfactant adminstartion. sedation will be provided with fentanyl. Surfactant will be given by the Sid
Sponsors
Rushikesh Gavhane
Eligibility
Inclusion criteria
Inclusion criteria: all preterm (less than 37 weeks) neonates admitted to the Neonatology Unit diagnosed with RDS requiring surfactant with lung ultrasound score more than 8
Exclusion criteria
Exclusion criteria: major congenital anomalies, the need for IPPV as resuscitation, Severe IVH (more than Gr III and above), Neonates who received the 1st dose of surfactant with either the INSURE or LISA method and refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| requirement of invasive mechanical ventilation in 72 hoursTimepoint: requirement of invasive mechanical ventilation in 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of administration of surfactant, to assess the adverse events (Bradycardia, desaturation, apnea) during surfactant administration, total duration of ventilation and oxygen requirement, requirement of inotropes, duration of hospitalisation and other major comorbidities such as PDA requiring treatment, IVH, NEC and ROP requiring treatment and BPDTimepoint: 36 weeks or death | — |
Countries
India
Contacts
Public ContactRushikesh Gavhane
Government Medical College and Hospital Chh. Sambhajinagar(Aurangabad)
Outcome results
None listed