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Study to compare pain relief and nerve block duration after adding dexmedetomidine to local anaesthetic during ultra sound guided nerve block for adults undergoing upper limb surgery

Comparative study of ultrasound guided supraclavicular branchial plexus block using zero point five percent bupivacaine ten millilitres and two percent lignocaine with adrenaline ten millilitres with injection dexmedetomidine one microgram per kilogram maximum fifty micrograms versus without dexmedetomidine as an adjuvant in adults undergoing upper limb surgery - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113424
Enrollment
60
Registered
2026-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: Dexmedetomidine as adjuvant to local anaesthetic for peripheral nerve block: Dexmedetomidine added to local anaesthetic solution during peripheral nerve block Control Intervention1: Loc

Sponsors

Sri Siddhartha Institute of Medical sciences and Research centre T Begur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 65 years. Either gender. ASA physical status I and II. Scheduled for elective surgery under peripheral nerve block. Willing to provide written informed consent.

Exclusion criteria

Exclusion criteria: Refusal to participate. Known allergy to dexmedetomidine or local anaesthetic agents. Severe hepatic, renal or cardiac disease. Coagulopathy or anticoagulant therapy. Infection at the block site. Neurological disorders affecting assessment of block characteristics. ASA physical status III and above.

Design outcomes

Primary

MeasureTime frame
Onset time of sensory blockTimepoint: Assesed every 3-5 minutes after completion of ultrasound guided supraclavicular branchial plexus block untill complete sensory block is achieved

Secondary

MeasureTime frame
Duration of sensory block Duration of motor block Time to first rescue analgesia Postoperative pain score using Visual Analogue Scale Hemodynamic parameters Heart rate Systolic blood pressure Diastolic blood pressure Respiratory rate Oxygen saturation Incidence of adverse events including bradycardia hypotension nausea vomiting respiratory depression local anesthetic toxicity & block failureTimepoint: From block completion until complete recovery Within 24 hours after surgery

Countries

India

Contacts

Public ContactDr Kaalvapalli Sravan Kumar Naidu

Sri Siddhartha Institute of Medical Sciences and Research , T Begur , Nelamangala , Bangalore -Rural

csuresh095@gmail.com9886253046

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026