Health Condition 1: G430- Migraine without aura
Conditions
Interventions
Intervention1: Atorvastatin: 20 mg,once daily for 12 weeks
Control Intervention1: Propranolol: 40 mg, once daily for 12 weeks
Sponsors
Chengalpattu medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients with age 18-45 years either sex, Newly diagnosed as episodic migraine according to ICHD-3, History of 4-14 migraine days per month, willing and able to consent and comply with study procedures
Exclusion criteria
Exclusion criteria: Chronic migraine or other chronic daily headache disorder, Use of migraine prophylactic medication within 1 month prior to enrolment, Medication overuse headache, History of ischemic heart disease, uncontrolled hypertension, heart block or bradycardia , severe heart failure, or significant arrhythmia , Active liver disease or unexplained persistent elevations of serum transaminases , Hypersensitivity/allergy to statins or to propranolol, Asthma or chronic obstructive pulmonary disease, Pregnancy or lactation, Uncontrolled psychiatric disorder, Other significant illness like renal failure, malignancy that could interfere with participation or safety
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Monthly migraine frequency will be assessed by review of Headache diaryTimepoint: 0,4,8,12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Migraine severity will be assessed by Visual Analog scale , Migraine-related disability will be assessed by Migraine Disability Assessment score Timepoint: 0,4,8,12 weeks | — |
Countries
India
Contacts
Public ContactDr Asha Loshini A
Chengalpattu medical college and hospital
Outcome results
None listed