Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Open Flap Debridement: After completion of phase 1 periodontal therapy and reevaluation after 4 to 6 weeks, eligible periodontal sites will undergo open flap debridement under local ana
Sponsors
Dr Dattraj Phadte
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with Stage III periodontitis presenting with horizontal suprabony bone loss. Presence of periodontal pockets with Probing Pocket Depth PPD of 5.4 mm or more after completion of Phase I periodontal therapy. Radiographic evidence of horizontal bone loss confirmed using standardized intraoral periapical radiographs. Plaque Index of 1 or less before surgical intervention. Systemically healthy patients or patients with controlled Type 2 diabetes mellitus with HbA1c of 7.5 percent or less. Patients willing to participate in the study and able to provide written informed consent. Patients having at least one or two periodontal sites fulfilling the study criteria.
Exclusion criteria
Exclusion criteria: Patients with uncontrolled diabetes mellitus with HbA1c greater than 7.5 percent. Smokers or tobacco users. Pregnant or lactating women. Patients with systemic diseases or conditions known to affect periodontal healing, such as immunocompromised conditions or bleeding disorders. Teeth with Grade III mobility. Patients with poor oral hygiene compliance. Patients unwilling to participate or unable to attend follow up visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Probing Pocket Depth PPD and Relative Attachment Level RAL following treatment with Open Flap Debridement alone, Open Flap Debridement with Hyaluronic Acid, and Open Flap Debridement with Advanced Platelet Rich Fibrin.Timepoint: baseline, 3 months and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in gingival thickness following treatment with Open Flap Debridement alone, Open Flap Debridement with Hyaluronic Acid, and Open Flap Debridement with Advanced Platelet Rich Fibrin.Timepoint: Baseline and 6 months;Early wound healing assessed using Early Wound Healing IndexTimepoint: 1 week;Change in Bleeding on Probing following treatmentTimepoint: Baseline, 3 months and 6 months;Change in Plaque Index following treatmentTimepoint: Baseline, 3 months and 6 months;Postoperative pain and patient discomfort assessed using the Visual Analog ScaleTimepoint: 1 week;Change in radiographic bone level assessed using standardised Intraoral Periodical Radiographs IOPA with gridTimepoint: Baseline and 6 months;Change in tooth mobility following treatmentTimepoint: Baseline and 6 months;Influence of Glycemic status HbA1c to be used to subgroup patientsTimepoint: Baseline | — |
Countries
India
Contacts
Public ContactDr James Samuel
Goa Dental College and Hospital
Outcome results
None listed