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Comparison of effectiveness of different methods of giving local anesthesia for pain control during root canal treatment in painful lower back teeth.

Comparative evaluation of anesthetic efficacy of inferior alveolar nerve block vs four site intraligamentary injection in mandibular molars with symptomatic irreversible pulpitis: A randomized clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113310
Enrollment
90
Registered
2026-07-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Inferior alveolar nerve block with 4 percent articaine: Conventional Inferior alveolar nerve block using 1.8 ml of 4 percent articaine with 1:100000 adrenaline administered once before

Sponsors

Pacific dental college and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Active pain in mandibular molars with baseline score greater than 54mm on HP-VAS Prolonged response to cold test and EPT that lingers on after removal of stimuli Lack of Periapical Radiolucency on X-ray, except in cases of PDL widening.

Exclusion criteria

Exclusion criteria: Presence of large periapical radiolucency Periodontal disease other than acute apical periodontitis History of medication affecting pain perception Allergy to Local anesthetic agents bleeding disorders pregnancy and lactation suspected substance abuse

Design outcomes

Primary

MeasureTime frame
Anesthetic success rate determined as completion of access cavity preparation and initial root canal instumentation with Heft Parker Visual Analogue Scale score less than or equal to 54 mm without the need of supplemental anesthesiaTimepoint: 15 minutes after administration of local anesthetic during access cavity preparation and initial root canal instrumentation—

Secondary

MeasureTime frame
Intraoperative pain score measure using HP-VASTimepoint: Baseline before anesthesia, 15 minutes after anesthetic administration, during access cavity preparation, & during initial root canal instrumentation.;Change in pain score from baseline HP-VAS measured before anesthesia to intraoperative HP-VASTimepoint: Baseline before anesthesia, 15 minutes after anesthetic administration, during access cavity preparation, & during initial root canal instrumentation.;Requirement for supplemental anesthesiaTimepoint: Assessed during access cavity preparation & initial root canal instrumentation following administration of the study anesthetic technique—

Countries

India

Contacts

Public ContactDr Pamita Agarwal

Pacific Dental College and Research Center

pamitaagarwal.1989@gmail.com9828797917

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026