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A Study Comparing Platelet Rich Fibrin and Placentrex Gel in Treating Gum Disease Without Surgery

Comparing Platelet Rich Fibrin PRF and Placentrex Gel as Adjuncts to Non-Surgical Periodontal Therapy in Chronic Periodontitis Patients : A Randomized Clinical Trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113253
Enrollment
8
Registered
2026-07-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Application of Placentrex gel after scaling and root planing: Scaling and Root planning will be performed for the patients followed by placement of Placentrex subgingivally into the p

Sponsors

Dr Sanjana V
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patient. Patient age ranging 18-60years. Patient who have agreed to participate in the study. Moderate periodontitis with attachment loss of 3 to 4 mm, probing depth lesser or equal to 6, and bleeding on probing in greater or equal to 2 quadrants

Exclusion criteria

Exclusion criteria: Smokers Pregnant and lactating women Systemic and debilitating diseases Use of antibiotics during the last six months. A previous unfavorable response to the study s products. Patients with bleeding disorders Patients taking antiplatelet therapy and anticoagulant therapy Patients with severe hepatic impairment or renal disease Subjects having a total platelet count lower than 150,000 per cubic mm. Subjects having medical conditions that compromised tissue healing osteoporosis, anemia, etc.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the clinical efficacy of PRF and Placentrex gel as adjuncts to scaling and root planing in the nonsurgical treatment of chronic periodontitis.Timepoint: baseline, 1 month, 3 months, and 6 months

Secondary

MeasureTime frame
Compare changes in probing pocket depth (PPD). Compare clinical attachment level (CAL) gain. Evaluate improvements in gingival index (GI) and bleeding on probing (BOP). Compare patient-reported outcomes (pain, satisfaction, comfort) Timepoint: baseline, 1 month, 3 months, and 6 months

Countries

India

Contacts

Public ContactDr M M Dayakar

KVG Dental College and Hospital

mmdayakar@yahoo.com09448167427

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026