Health Condition 1: F209- Schizophrenia, unspecified Health Condition 2: F209- Schizophrenia, unspecified
Conditions
Interventions
Intervention1: Dexmedetomidine: Intervention-Dexmedetomidine 1 microgram per kg intravenous infusion over 15 minutes administered 30 minutes before ECT followed by Standard anaesthesia with propofol 1
Sponsors
Dr Robina Makker
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with Schizophrenia as per DSM5,scheduled for ECT ,aged 18 to 65 years and categorised as American Society of Anaesthesiologist ASA physical status classification 1 to 3
Exclusion criteria
Exclusion criteria: Patient refusal Heart rate less than 65 per minute Baseline systolic blood pressure less than 100mmhg ECG abnormalities ASA grade 4 or more Pregnant female Patient with substance use disorder except nicotine and caffeine Patients in whom succinylcholine is contraindicated Patients with known allergy to one of the drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic stability- heart rate , systolic , diastolic and mean arterial blood pressure , oxygen saturation and post ictal agitationTimepoint: From beginning of dexmedetomidine infusion, at the end of infusion , during ECT , 1 minute , 3 minute , 5 minute , 10 minute , 15 minute and 30 minutes post ECT | — |
Secondary
| Measure | Time frame |
|---|---|
| Post ictal agitation Timepoint: observed till 30 minutes post ECT.;Motor seizure durationTimepoint: observed during ECT;Incidence of side effects -bradycardia , hypotension , sedation Timepoint: from beginning of infusion to 30 minutes post ECT;Recovery time from anaesthesiaTimepoint: observed post ECT for upto 30 minutes | — |
Countries
India
Contacts
Public ContactDr Robina Makker
Department of Anaesthesia, Shri Guru Ram Rai Institute of medical and health sciences
Outcome results
None listed