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Using Ultrasound of Chest Muscle to Predict Successful Removal of Breathing Tubes in Patients with Pesticide Poisoning.

The Utility of Diaphragmatic Thickness Fraction Measured by Bedside Ultrasonography for Predicting Extubation Success in Patients with Organophosphate Poisoning: A Prospective Observational Study. - Nil

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/07/113235
Enrollment
35
Registered
2026-07-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T600- Toxic effect of organophosphate and carbamate insecticides

Interventions

Intervention1: Nil: Nil

Sponsors

Postgraduate Institute of Medical Education and Research, Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with confirmed Organophosphate poisoning with age greater or equal to 18 years, Patients requiring invasive mechanical ventilation, Patients undergoing spontaneous breathing trial prior to extubation, Provision of informed consent by legally acceptable representative, Excessive secretions.

Exclusion criteria

Exclusion criteria: Patients aged less than 18 years. Pregnant patients. Patients with pre-existing neuromuscular disease affecting diaphragmatic function. Patients with known diaphragmatic paralysis or chronic respiratory failure. Patients with significant chest wall deformity. Patients with cervical spinal cord injury. Patients with poor ultrasonographic window preventing adequate diaphragm visualization. Patients extubated accidentally or self-extubated. Patients refusing consent. ARDS, Morbid obesity, Burns, Trauma, Post operative.

Design outcomes

Primary

MeasureTime frame
To assess the weaning outcome at Forty eight hours categorized as either successful extubation remaining free from any type of mechanical ventilatory support or Extubation failure which includes reintubation, non invasive positive pressure ventilation and death.Timepoint: Forty eight hours post extubation, patient is to be observed for primary outcome.—

Secondary

MeasureTime frame
Comparison of diaphragmatic thickness fraction with Rapid Shallow Breathing Index & Maximal Inspiratory Pressure for prediction of extubation success. To find out an Optimal cutoff value of diaphragmatic thickness fraction for predicting successful extubation. To explore association between Pre extubation Diaphragmatic Thickness Fraction & Duration of mechanical ventilation, ICU length of stay, total hospital stay. Timepoint: Fourteen Days—

Countries

India

Contacts

Public ContactDr Saurabh C Sharda

Postgraduate Institute of Medical Education and Research, Chandigarh

saurabhcsharda@gmail.com01722756670

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026