Health Condition 1: K831- Obstruction of bile duct
Conditions
Interventions
Intervention1: Administration of Propofol,Ketamine and Dexmedetomidine in icteric and non icteric patients: To evaluate whether icteric patients exhibit a prolonged arousal gap following
Propofol-Keta
Sponsors
Department of Anaestheisology
Eligibility
Inclusion criteria
Inclusion criteria: Aged 18-70 years, ASA Physical Status I,II and III and undergoing elective interventional endoscopic procedures
Exclusion criteria
Exclusion criteria: Pre-existing encephalopathy (Child-Pugh Class C) Electrolyte Imbalance Pregnancy Chronic opioid or benzodiazepine use Sedation converted to General anaesthesia Emergency interventional endoscopic procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the arousal gap following Propofol ketamine dexmedetomidine sedation in icteric versus non-icteric patients undergoing interventional endoscopyTimepoint: immediate post procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To correlate serum bilirubin levels with duration of arousal gap. 2. To assess recovery profiles using standardized sedation & recovery scores. 3. To evaluate incidence of delayed recovery-related adverse events (airway obstruction, desaturation, need for stimulation). 4. To study hemodynamic stability during & after PKD sedation in icteric patientsTimepoint: Immediate Post procedure (Time since stoppage of Drug to awakening of patient) | — |
Countries
India
Contacts
Public ContactAnjuman Chander
Graphic Era Institute of Medical Sciences
Outcome results
None listed