Comparing the effects when Vitamin C is added to titanium tubes with patients blood to create a membrane that may or maynot treat receeding gums

Clinical evaluation of Vitamin C infused titanium platelet rich fibrin versus titanium platelet rich fibrin in the management of gingival recession using coronally advanced flap: A Randomized controlled trial. - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/113181

Enrollment

Registered

2026-06-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K060- Gingival recession

Interventions

Intervention1: Vitamin C infused Titanium Platelet rich fibrin: 2500 g pure Vitamin C (Pharmaceutical grade) will be added to 10ml of fresh blood that is withdrawn from patient into Medical graded Tit

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patient. Patient age ranging 18-50years. Patient who have agreed to participate in the study. Patient with Cairo s Type I Gingival recession defect without mobility

Exclusion criteria

Exclusion criteria: Pregnant and Lactating mothers. Smokers and Alcoholic patients. Patients with Kidney or Liver disease. Patient with probing pocket depth greater than 3mm. Patients who have undergone any periodontal treatment within last 6 months. ients who are under medications. Malpositioned teeth that needs to be treated. Patients with platelet count less than 2,000,000per cubic mm Patients with Cairo s Type II & III gingival recession sites Patients with absence of adjacent teeth where CAF would rest

Design outcomes

Primary

Measure	Time frame
To compare the clinical efficacy of vitamin C infused Titanium platelet-rich fibrin (T-PRF) membrane with conventional T-PRF membrane in root coverage procedures for the management of gingival recession.Timepoint: baseline, 1 month and 3 months	—

Secondary

Measure	Time frame
To compare the percentage of root coverage achieved using vitamin C infused T-PRF membrane and conventional T-PRF membrane alone. To compare the reduction in gingival recession depth between two groups. To compare the gain in clinical attachment level following treatment in both groups. To evaluate and compare changes in the width of keratinized gingiva between the two groups. To assess and compare soft tissue healing and clinical stability during the follow-up period. Timepoint: Baseline, 1 month and 3 months	—

Measure

Time frame

To compare the percentage of root coverage achieved using vitamin C infused T-PRF membrane and conventional T-PRF membrane alone. To compare the reduction in gingival recession depth between two groups. To compare the gain in clinical attachment level following treatment in both groups. To evaluate and compare changes in the width of keratinized gingiva between the two groups. To assess and compare soft tissue healing and clinical stability during the follow-up period. Timepoint: Baseline, 1 month and 3 months

—

Countries

India

Contacts

Public ContactDr M M Dayakar

KVG Dental College and Hospital

mmdayakar@yahoo.com09448167427

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026