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Effectiveness and safety of Sugammadex versus Neostigmine with Glycopyrrolate in reversing muscle relaxation following general anaesthesia

Efficacy and safety of Sugammadex Vs Neostigmine - Glycopyrrolate in Reversing Neuro muscular blockade in patients undergoing surgeries under General Anaesthesia - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/113155
Enrollment
104
Registered
2026-06-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K319- Disease of stomach and duodenum, unspecified

Interventions

Intervention1: Injection Sugammadex : injection Sugammadex 2mg/kg will be given Intravenously & time duration for reversal of neuromuscular blockage will be recorded Control Intervention1: Injection

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients under ASA grade I, II. Patients scheduled for surgeries to be performed under general anaesthesia. Patients willing to sign written informed consent

Exclusion criteria

Exclusion criteria: Patients with ASA Grade III & IV. Patients with known allergy any of the study drugs. Patients receiving Neuromuscular blocking agents other than Inj. Vecuronium

Design outcomes

Primary

MeasureTime frame
Time to achieve adequate neuromuscular recovery.Timepoint: Time from study drug administration (at the appearance of second twitch i.e T2 after last dose of vecuronium) to tracheal extubation (TOFR = 0.9)

Secondary

MeasureTime frame
Incidence of residual neuromuscular blockade (RNMB)Timepoint: At extubation and on arrival in post op recovery room;Time to orientationTimepoint: At 5, 10, 15 min post-reversal

Countries

India

Contacts

Public ContactDr Tejas Pangale

Parul Institute of Medical Sciences and Research

dr.a.m.chhaya@gmail.com9824233654

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026