Clinical evaluation of interappointment pain using two different endodontic irrigants in teeth with necrotic pulp

Evaluation of calcium hypochlorite and sodium hypochlorite irrigation on interappointment pain during root canal treatment in necrotic teeth a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/113101

Enrollment

Registered

2026-06-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Calcium hypochlorite: Evaluation of interappointment pain at 24hours 48hours 72hours and 7days Control Intervention1: Sodium hypochlorite: Evaluation of interappointment pain at 24hours

Eligibility

Inclusion criteria

Inclusion criteria: Patients age between 18 to 45 years Patients with no systemic diseases and conditions Teeth presenting non vital pulp and radiographic evidence of apical periodontitis

Exclusion criteria

Exclusion criteria: Teeth with abnormal root morphology Patients who had a history of sensitivity or adverse reactions to any of the medication Retreatment cases Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
To evaluate the intensity of interappointment pain after using two different endodontic irrigants using visual analog scaleTimepoint: baseline 0 months	—

Secondary

Measure	Time frame
To evaluate the incidence of interappointment pain after using two different endodontic irrigantsTimepoint: 24 hours 48 hours 72 hours 7 days	—

Countries

India

Contacts

Public ContactNeehar Sai Kiran Pendem

GITAM dental college and hospital

raavi.ravi13@gmail.com9155717777

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026