Health Condition 1: D509- Iron deficiency anemia, unspecified
Conditions
Interventions
Intervention1: Oral iron supplementation alternate day: Oral elemental iron 3 mg per kg per dose administered on alternate days for a total duration of 12 weeks in children with iron deficiency anemia
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 6 months to 12 years Diagnosed with Iron Deficiency Anemia defined by Hemoglobin below WHO age appropriate cut offs Peripheral smear showing microcytic hypochromic anemia Low MCV MCH ratio increased RDW Low Serum ferritin less than 15 ng per mL Nutritional anemia suspected as the primary cause Attending OPD and IPD Dept Of Paediatrics Trichy SRM Medical College Informed written consent obtained from parent and guardian
Exclusion criteria
Exclusion criteria: Children on iron therapy or blood transfusion within the past 3 months Known malabsorption syndromes celiac disease IBD Children with significant comorbidities making follow up difficult Refusal of parental guardian consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in hemoglobin concentration measured as change from baseline to 12 weeks.Timepoint: Baselin, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal tolerability will be assessed using a structured caregiver questionnaire documenting symptoms such as nausea, vomiting, abdominal pain, constipation and diarrhea at baseline, 4 weeks and 12 weeks. Treatment compliance will be assessed at 4 weeks and 12 weeks using the syrup bottle method and expressed as percentage of prescribed dose and categorized as good or poor adherence. Outcomes will be reported as proportion of children with adverse effects, severity distribution, mean compliance and proportion with good adherence. Treatment discontinuation and loss to follow up will also be recorded.Timepoint: Baseline, 4 weeks, 12 weeks | — |
Countries
India
Contacts
Public ContactDr M Aravind
Trichy SRM Medical College Hospital and Research Center
Outcome results
None listed