Health Condition 1: - Health Condition 2: G891- Acute pain, not elsewhere classified
Conditions
Interventions
Intervention1: Transdermal Buprenorphine Patch: Transdermal buprenorphine patch applied preoperatively for postoperative analgesia in adult patients undergoing elective cardiac surgery under general a
Sponsors
CAREER INSTITUE OF MEDICAL SCIENCES AND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged 18 to 75 years Patients undergoing elective cardiac surgery under general anaesthesia ASA physical status 2 and 3 Patients willing to provide informed written consent
Exclusion criteria
Exclusion criteria: Known allergy to buprenorphine or opioids Severe hepatic or renal dysfunction Chronic opioid use or opioid dependence Patients with psychiatric illness or inability to understand pain scoring Emergency cardiac surgery Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity measured using Visual Analog Scale in adult patients undergoing cardiac surgery receiving transdermal buprenorphine patch.Timepoint: At 2 hours 6 hours 12 hours 24 hours and 48 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include total rescue analgesic consumption during the first 72 hours after surgery, incidence of opioid-related adverse effects such as nausea, vomiting, sedation and respiratory depression, changes in hemodynamic parameters (heart rate and mean arterial pressure), and overall patient satisfaction with postoperative pain relief, which will be assessed during the first 72 hours following surgeryTimepoint: 24 h, 48 h, 72 h post-operativel | — |
Countries
India
Contacts
Public ContactSHAIK ABDUL SALAM
CAREER INSTITUTE OF MEDICAL SCIENCES AND HOSPITAL
Outcome results
None listed