Comparison of omega 3 fatty acids with normal saline to reduce inflammation in robotic surgeries

A Randomized Control Trial Comparing the Effects of Omega-3 Fatty Acid Supplementation on Postoperative Cognitive Dysfunction (POCD) in Patients Undergoing Radical Robotic Prostatectomy (RRP) Using Peripheral Insulin Resistance as a Surrogate Marker of Inflammation - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112939

Enrollment

120

Registered

2026-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Omega 3 Fatty Acids: Supplementation will begin 1 day before surgery and continue until 3 days postoperatively. Group A will receive 0.2ml per kg of Omega 3 Fatty Acids on POD 0,POD 1,2

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing elective radical robotic prostatectomy ASA physical status I to III Educated upto Grade 5 and above.

Exclusion criteria

Exclusion criteria: Refusal to give consent Pre existing neurodegenerative disease Patients on steroid therapy Chronic use of omega 3 supplements or anti inflammatory drugs Known allergy to fish oil

Design outcomes

Primary

Measure	Time frame
Incidence and severity of POCD Timepoint: Baseline,2 weeks, 3months	—

Secondary

Measure	Time frame
Measurement of inflammatory markersTimepoint: The day of surgery as baselines Post operative day 1,2,3	—

Countries

India

Contacts

Public ContactDr Janaki Padmakumar

SRI SHANKARA CANCER HOSPITAL AND RESEARCH CENTRE

janu234@gmail.com9535619079

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026