Comparison of intravenous maintenance fluids with and without dextrose in pediatric surgical patients.

A comparative study to evaluate intraoperative blood glucose levels in pediatric patients undergoing major surgeries with or without dextrose supplementation under general anaesthesia with caudal analgesia at S.M.S. Medical College, Jaipur - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112935

Enrollment

Registered

2026-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A (Intervention): Ringers Lactate with 1% Dextrose administered as maintenance fluid based on the childs weight according to the Holliday-Segar formula. Control Intervention1: Gro

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pediatric patients with age ranging between 6 months to 8 years of either sex. 2. Scheduled for elective major surgery (e.g., abdominal, urological, or orthopedic procedures) 3. ASA Physical Status I or II. 4. Informed written consent obtained from the parent or legal guardian.

Exclusion criteria

Exclusion criteria: 1. Presence of endocrine disorders or known metabolic/glucose regulation disorders. 2. Emergency surgery 3. Pre-existing neurological, cardiac, hepatic, or renal disease. 4. Contraindications to caudal block (e.g., bleeding diathesis, infection at the injection site, spinal anomaly) 5. Patients on steroids or medications affecting blood glucose metabolism.

Design outcomes

Primary

Measure	Time frame
Mean difference in intraoperative blood glucose levels (mg/dL) at different time intervals among the study groups.Timepoint: Baseline (pre-induction), and intraoperatively at 30, 60, 90, and 120 minutes.	—

Secondary

Measure	Time frame
Hemodynamic Changes: Evaluation and comparison of Heart Rate (HR), Mean Arterial Pressure (MAP), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), and SpO2Timepoint: Baseline, post-premedication, post-induction, 5 mins post-intubation, post-block, 5 mins post-block, 30 min, 60 min, 90 min, and 120 min.;Glycemic Events: Incidence of hypoglycemia (blood glucose less than 60mg/dL) and hyperglycemia (blood glucose greater than 180mg/dL)Timepoint: At designated 30-minute sampling intervals up to 120 minutes.;Intervention Requirement: Documentation of any specific medical interventions required to correct hypoglycemic or hyperglycemic episodes.Timepoint: NIL	—

Measure

Time frame

Hemodynamic Changes: Evaluation and comparison of Heart Rate (HR), Mean Arterial Pressure (MAP), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), and SpO2Timepoint: Baseline, post-premedication, post-induction, 5 mins post-intubation, post-block, 5 mins post-block, 30 min, 60 min, 90 min, and 120 min.;Glycemic Events: Incidence of hypoglycemia (blood glucose less than 60mg/dL) and hyperglycemia (blood glucose greater than 180mg/dL)Timepoint: At designated 30-minute sampling intervals up to 120 minutes.;Intervention Requirement: Documentation of any specific medical interventions required to correct hypoglycemic or hyperglycemic episodes.Timepoint: NIL

—

Countries

India

Contacts

Public ContactDr Bhawna Gupta

SMS medical college and attached hospitals

pratibha.rathore3@gmail.com9414446473

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026