This topic compares two ways of giving lignocaine to numb the airway during awake fibre-optic intubation

A comparative study of nebulization versus atomization with four percent lignocaine for topical airway Anesthesia in awake fibre optic intubation - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112885

Enrollment

Registered

2026-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: X- New Technology

Interventions

Intervention1: Using four percent lignocaine in nebulization and atomization: Nebulization4 percentage lignocaine via oxygen-driven nebulizer for airway topical anesthesia before awake fiberoptic intu

Eligibility

Inclusion criteria

Inclusion criteria: Patients planned for head and neck cancer surgery Patients of all gender age of 18 to 65 years BMI less than 35KG per meter square American society of anesthesiologists (ASA) physical status II and III Patient with anticipated difficult airway Patient given consent for awake fiber optic nasal intubation

Exclusion criteria

Exclusion criteria: Any bleeding disorder or patient on anticoagulants. Patients with nasal pathology. Patients having drug allergy. Pregnant and lactating females Patients with uncontrolled hypertension andbradyarrhythmia and psychiatric illness

Design outcomes

Primary

Measure	Time frame
To asses and compare the patient cooperation and comfort score between two groups 40 people each groupTimepoint: To asses and compare the patient cooperation and comfort score between two groups during baseline ,during intubation , 1 minute after intubation ,3 minute after intubation ,5 minute after intubation ,10 minute after intubation.	—

Secondary

Measure	Time frame
To assess intubation time from insertion of fiberscope into the nostril to confirmation of tracheal intubation with capnography To assess quality and adequacy of airway anaesthesia (as judged by intubation score, cough and gag reflex). To assess hemodynamic responses during intubation. To assess incidence of complications such as coughing, desaturation, or signs of local anesthetic toxicityTimepoint: During intubation 1 min after intubation 3 min after intubation 5 min after intubation 10 min after intubation	—

Measure

Time frame

To assess intubation time from insertion of fiberscope into the nostril to confirmation of tracheal intubation with capnography To assess quality and adequacy of airway anaesthesia (as judged by intubation score, cough and gag reflex). To assess hemodynamic responses during intubation. To assess incidence of complications such as coughing, desaturation, or signs of local anesthetic toxicityTimepoint: During intubation 1 min after intubation 3 min after intubation 5 min after intubation 10 min after intubation

—

Countries

India

Contacts

Public ContactDr Namita Gupta

Mahatma Gandhi university of medical science and technology

drnamita2007@gmail.com9462083676

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026