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Comparing Efficacy of Sugammadex with Neostigmine in Reversing Vecuronium Muscle Relaxant In Obese Patients.

Comparison Of Sugammadex And Neostigmine Reversal For Vecuronium In Obese Patients Posted for Elective Surgery Under General Anaesthesia - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112883
Enrollment
40
Registered
2026-06-17
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Sugammadex: Sugammadex is a modified gamma cyclodextrin with eight identical hydroxyl chains bound together to create a ring with a hydrophobic core and a hydrophilic outer surface res

Sponsors

Dr B Chandini Reddy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Aged 18-80 years. 2) ASA II and above. 3) Obese patients undergoing general anaesthesia and who received vecuronium for neuromuscular block and sugammadex or neostigmine for reversal of neuromuscular block. 4) Surgery lasting for not more than 3 hours. 5) Elective surgery.

Exclusion criteria

Exclusion criteria: 1)Patients allergic to study drugs. 2)Pregnant and breast feeding. 3)Patients having impaired pulmonary function. 4)Refusal of consent. 5)Psychiatric patients. 6)Any intra operative adverse events.

Design outcomes

Primary

MeasureTime frame
To Compare The Efficacy Of Sugammadex Vs Neostigmine In Reversing Muscle Relaxant Vecuronium In Obese Patients Undergoing Elective Surgery Under General Anaesthesia.Timepoint: 1 year 6 months

Secondary

MeasureTime frame
To Compare The Efficacy Of Sugammadex Vs Neostigmine In Preventing Postoperative Nausea And Vomiting In Obese Patients Undergoing Elective Surgery Under General Anaesthesia.Timepoint: 1 year 6 months

Countries

India

Contacts

Public ContactDr Sarika M Shetty

Jss Hospital

drsarikamshetty@yahoo.com9900129069

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026