Evaluation of a Novel RGD Functionalized Hydrogel Along with Root Coverage Surgery for the Treatment of Gum Recession

A Randomized Controlled Clinical Study on Comparative Assessment of Arginylglycylaspartic Acid RGD Peptide Functionalized Sodium Alginate Hydrogel as an Adjunct to Coronally Advanced Flap with Connective Tissue Graft in the Treatment of Gingival Recession - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112853

Enrollment

Registered

2026-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K05- Gingivitis and periodontal diseases

Interventions

Intervention1: RGD peptide: Test group:-The connective tissue graft will be uniformly coated with RGD peptide loaded sodium alginate hydrogel and positioned over the denuded root surface Edit || Delet

Eligibility

Inclusion criteria

Inclusion criteria: 1 Single two teeth associated with Cairo RT 1 or 2 gingival recession defects 2 Patients aged 18 to 50 years 3 Probing depth less than or equal to 3mm at the recession site 4 Adequate plaque control and patient compliance

Exclusion criteria

Exclusion criteria: 1 Chronic smokers 2 Patients who are unwilling to participate in the study 3 Pregnant and lactating mothers 4 Patients using drugs which may be containdication for periodontal surgery

Design outcomes

Primary

Measure	Time frame
Recession depth Timepoint: BASELINE 3 MONTHS 6 MONTHS	—

Secondary

Measure	Time frame
Pocket Depth Clinical Attachment Level Recession Width Width of Keratinized Tissue Thickness of Keratinized TissueTimepoint: BASELINE 3 MONTHS 6 MONTHS	—

Countries

India

Contacts

Public ContactDr S Vidya Sagar

Kamineni Institute of dental sciences

drsagarperio@gmail.com9989117747

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026