A Study to Determine Whether Adding Dexamethasone to Local Anaesthesia Reduces Pain During Fistula Surgery in Patients with Kidney Failure

A Randomized Controlled Trial Assessing the Analgesic Efficacy of Lignocaine with Low-Dose Dexamethasone in Radiocephalic AV Fistula Creation in ESKD Patients - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112788

Enrollment

Registered

2026-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N17-N19- Acute kidney failure and chronic kidney disease Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Lignocaine plus dexamethasone group: Patients in group LD (n = 40) will receive 2% lignocaine (4 mg/kg) and 4 mg preservative-free dexamethasone diluted in 2 mL normal saline. Control I

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either gender, aged 18 60 years, scheduled for radio cephalic arteriovenous fistula (AVF) creation

Exclusion criteria

Exclusion criteria: diabetic mellitus, uncooperative patients or patient refusal, clinically significant coagulopathy, presence of upper extremity peripheral neuropathy/neurological disorder, presence of local site infection, history of a known allergy to local anaesthetics.

Design outcomes

Primary

Measure	Time frame
Intraoperative pain intensity measured using the Visual Analogue Scale at 45 minutes after the start of radiocephalic arteriovenous fistula creation surgeryTimepoint: 45 minutes after the start of surgery	—

Secondary

Measure	Time frame
Time to first rescue analgesic administrationTimepoint: every 15 minutes	—

Countries

India

Contacts

Public ContactABHILASH CHANDRA

Dr RMLIMS

acn393@gmail.com08176007206

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026