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Comparing How Bacteria Grow on Clear Aligners Over Different Time Periods

A COMPARATIVE ANALYSIS OF MICROBIAL COLONIZATION ON CLEAR ALIGNERS AT DIFFERENT TIME INTERVALS :An Ex Vivo Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/06/112779
Enrollment
36
Registered
2026-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: Dr. Apurva K. Srivastava: Professor And Head Department of Microbiology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences

Sponsors

Dr Pragya Acharya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Patients undergoing InvisalignTM clear aligner treatment. b) Patients with no oral and systemic disease. c) Patients having no deleterious habits. d) Patients have not undergone antibiotics/antimicrobials therapy in past 3 months. e) Aligner samples free from any visible manufacturing defects, warping, or discoloration. f) Patient oral cavity should be (OHI-S:fair) and low DMFT grading before the start of the study and the patient should be encouraged for good oral hygiene.

Exclusion criteria

Exclusion criteria: a) Aligner samples with surface irregularities, contamination, cracks, or distortions resulting from fabrication or handling errors. b) Patients having high caries risk. c) Patients with poor periodontal condition.

Design outcomes

Primary

MeasureTime frame
There is a significant difference in Streptococcus mutans colonization on clear aligners at different time intervals.Timepoint: at 7th , 10th and 14th day from start of wearing that particular aligner

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactPragya Acharya

Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow

Pragya29forever@gmail.com9319226951

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026