Health Condition 1: I639- Cerebral infarction, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Pinky
Eligibility
Inclusion criteria
Inclusion criteria: Adults more than equal to 18 years till 80 years of either sex with acute ischemic stroke presenting within 24 hour of symptom onset. At least one insonatable intracranial artery for TCD examination via transtemporal acoustic window.
Exclusion criteria
Exclusion criteria: Intracerebral bleed including intracranial hemorrhage Subarachnoid hemorrhage SAH traumatic brain injury and Cerebral venous thrombosis Patients with poor temporal bone acoustic windows preventing MES monitoring. Pre-stroke severe disability mRS more than 2 Major comorbidities affecting prognosis eg advanced malignancy end-stage heart failure with expected survival less than 3 months. Refusal or inability to provide consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with poor functional outcome mRS more than equal to 3 according to MES presence and persistence. Timepoint: 3 months (90 7 days) after stroke onset/enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome 1 MES Persistence as Predictor of Recurrence. Association between persistent MES (detected up to 72 hours) and recurrent ischemic stroke. Outcome 2 MES Burden and Stroke Severity Association between MES burden and stroke severity measured using NIHSS. Outcome 3 MES Burden Across Treatment Groups Comparison of MES burden among IVT, EVT, IVT+EVT, and medical therapy groups. Outcome 4 MES Burden and TOAST Classification Association between MES burden and TOAST stroke subtype. Timepoint: Time Point secondary outcome 1 Within 3 months of enrollment. Time Point of secondary outcome 2 At baseline, discharge, and 3 months. Time Point of secondary outcome 3 During hospitalization baseline to 72 hours. Time Point of secondary outcome 4 From hospitalization baseline. | — |
Countries
India
Contacts
Public ContactPinky
Hospital
Outcome results
None listed