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Comparing Dexmedetomidine and Nalbuphine for Pain Relief in Children Undergoing Hernia Surgery

Ultrasound guided caudal analgesia in children undergoing herniotomy surgeries under general anesthesia A randomized double blind study comparing Dexmedetomidine and Nalbuphine as adjuvant to 0.25% Ropivacaine - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112740
Enrollment
80
Registered
2026-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Ultrasound guided Caudal block with 0.75 ml/kg of 0.25% Ropivacaine and 1 mcg/kg Dexmedetomidine: To determine the duration of analgesia FLACC scores sedation score Total analgesic cons

Sponsors

Dr Shamya Rose Aseervatham
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children between 2-6 years of age of either sex belonging to ASA I & II of weight less than 20 kgs undergoing elective herniotomy surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patients with known allergies to study medication 2.Patients with contraindications to caudal block 3.Infection at injection site 4.Patients with coagulopathies or on anticoagulation therapy 5.Patients on chronic analgesic therapy

Design outcomes

Secondary

MeasureTime frame
1.To assess haemodynamics intraoperatively and postoperatively upto 24 hrs between two groups. 2.To assess adverse effects between two groups. 3.To examine the level of sedation postoperatively between two groups. 4.To compare the severity of pain in both groups Timepoint: Every hour postoperatively upto 24 hours

Primary

MeasureTime frame
To determine the duration of analgesia between Dexmedetomidine with Ropivacaine and Nalbuphine with Ropivacaine by USG caudal blockTimepoint: Every hour postoperatively upto 24 hours

Countries

India

Contacts

Public ContactDr Raghavendra Prasad

Government Medical College Kadapa

saya_knl@yahoo.com8919097416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026