Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Total Intravenous Anaesthesia: Participants randomized to this group after induction with propofol 2-2.5mg/kg will receive maintenance of general anesthesia using intravenous propofol i
Sponsors
Jawaharlal Nehru Medical College, Aligarh Muslim University
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged 18-65 years. Patients of either sex. Patients scheduled for elective laparoscopic cholecystectomy under general anaesthesia. ASA status 1 or 2 Patients willing to participate and providing written informed consent.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Middle Cerebral Artery (MCA) blood flow velocity using Transcranial doppler (cm/s)Timepoint: Middle Cerebral Artery (MCA) blood flow velocity using Transcranial doppler (cm/s) T0- Before administration of anaesthesia. T1- 5 minutes after CO2 insufflation in reverse trendelenburg position. T2-5 minutes after Pneumoperitoneum termination in reverse Trendelenburg position. T3- Post extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic Parameters Heart rate Systolic Blood Pressure Diastolic Blood Pressure Mean Arterial Pressure Spo2 End tidal CO2 MAC (desflurane group)Timepoint: Every 5 minutes intraoperatively until completion of surgery. | — |
Countries
India
Contacts
Public ContactProf Obaid Ahmed Siddiqui
Jawaharlal Nehru Medical College and Hospital AMU, Aligarh
Outcome results
None listed