Comparing Fractional Carbon Dioxide Laser Plus Amorolfine Nail Lacquer with Amorolfine Nail Lacquer Alone in Patients with Fungal Nail Infection

COMPARATIVE STUDY OF FRACTIONAL CARBON DIOXIDE LASER COMBINED WITH AMOROLFINE NAIL LACQUER AND AMOROLFINE NAIL LACQUER ALONE IN THE TREATMENT OF ONYCHOMYCOSIS - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112721

Enrollment

Registered

2026-06-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L608- Other nail disorders

Interventions

Intervention1: Fractional Carbon Dioxide Laser combined with Amorolfine Nail Lacquer: Fractional carbon dioxide laser sessions at defined intervals along with topical amorolfine nail lacquer applicati

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing to give written informed consent will be taken for the study. Patients who have not taken systemic or topical anti-fungal treatment in the past 3 months

Exclusion criteria

Exclusion criteria: History of topical or systemic anti-fungal drug use in the past 3 months Pregnancy and breastfeeding Any other nail infection or paronychia Patient unwilling to give written informed consent

Design outcomes

Primary

Measure	Time frame
Clinical cure assessed by improvement in nail discoloration, thickening and distortion using Onychomycosis Severity IndexTimepoint: 3 months	—

Secondary

Measure	Time frame
Mycological cure assessed by negative PAS stain and KOH microscopyTimepoint: 3 months;Patient satisfaction and recovery assessmentTimepoint: 3 months;Adverse events including pain, swelling, erythema and scarringTimepoint: During treatment and at follow up visits	—

Countries

India

Contacts

Public ContactRiya Tyagi

Muzaffarnagar Medical College And Hospital

vineetrelhan@gmail.com9910086636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026