FindTrial
Sign In

Comparison of Ketamine with Etomidate for Peri-Intubation Hemodynamic Instability in Patients Undergoing Emergency Intubation.

Ketamine versus Etomidate for Peri-Intubation Hemodynamic Instability in Adult Critically Ill Patients Undergoing Emergency Endotracheal Intubation in the Emergency Department: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112698
Enrollment
1006
Registered
2026-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: U072- COVID 19 virus not identified

Interventions

Intervention1: Ketamine Group: Group A: Ketamine Group: Ketamine 1 2 mg/kg IV bolus for induction Intervention2: Group A : Ketamine Group: Ketamine Group: Ketamine 1 2 mg/kg IV bolus Control Intervent

Sponsors

Dr Vishal Vaibhaw
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than or equal to 18 years Critically ill patients requiring emergency endotracheal intubation in the emergency Indication for rapid sequence intubation

Exclusion criteria

Exclusion criteria: Cardiac arrest at presentation Pregnancy Known adrenal insufficiency or chronic systemic steroid use Known allergy or contraindication to ketamine or etomidate Use of induction agents other than ketamine or etomidate

Design outcomes

Primary

MeasureTime frame
Blood pressure and heart rateTimepoint: Just prior to induction , immediately post induction, every 5 minutes post intubation until 30 minutes.—

Secondary

MeasureTime frame
7-day & 28-day mortality Vasopressor duration ICU length of stay Duration of mechanical ventilation Change in SOFA score at 24 & 48 hours Adverse airway events (hypoxia, aspiration, multiple attempts)Timepoint: 7 Day 28 Day—

Countries

India

Contacts

Public ContactVishal Vaibhaw

AIIMS Patna

drvishal11645@aiimspatna.org8987536845

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026