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A study to find out which is more effective between lignocaine nebulisation versus topical lignocaine spray for the attenuation of hemodynamic response during laryngoscopy and endotracheal intubation in patients scheduled for surgery under general anaesthesia.

A randomized comparative study to evaluate the effectiveness of Lignocaine nebulisation versus topical lignocaine spray for attenuation of hemodynamic response to laryngoscopy and endotracheal intubation in patients schedule for elective surgery under general Anaesthesia at SMS Medical College, Jaipur. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112685
Enrollment
60
Registered
2026-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 4% Lignocaine spray: Patients will receive 4% lignocaine nebulisation (1.5 mg/kg), diluted to make 10ml volume by simple nebulisation face mask 15 minutes before induction of anaesthesi

Sponsors

SMS medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient undergoing elective surgical procedures under general anaesthesia requiring endotracheal intubation. Patients willing to give informed and written consent. Adult patients BMI 18kg/m2- 30kg/m2 Patients belonging to American Society of Anaesthesiologists (ASA) grade I & II.

Exclusion criteria

Exclusion criteria: Patient with any contraindications or history of hypersensitivity to amide local anaesthetics. Patients with uncontrolled hypertension, hepatic or renal disease, seizure disorder. Pregnant/lactating women. Anticipated difficult intubation. Patient who is a part of any other study.

Design outcomes

Primary

MeasureTime frame
To assess and compare the change in hemodynamic parameters (HR,SBP,DBP,MAP) from baseline at different time intervals between the study groups.Timepoint: To assess and compare the change in hemodynamic parameters (HR,SBP,DBP,MAP) from baseline at different time intervals between the study groups.

Secondary

MeasureTime frame
To assess and compare the proportion of patients who develop side effects ( if any).Timepoint: Monitoring for side effects till 24hrs after the completion of surgery.

Countries

India

Contacts

Public ContactDivya Bhatnagar

SMS medical college and attached hospital

kanchan2371@yahoo.com8107872222

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026