A study comparing two local anaesthetics (levobupivacaine and ropivacaine) used for shoulder and upper arm surgery to assess their effect on breathing and pain relief

A Randomized double study comparing Levobupivacaine and Ropivacaine in ultrasound guided interscalene brachial plexus block on Hemi diaphragmatic paresis - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112613

Enrollment

Registered

2026-06-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S422- Fracture of upper end of humerus Health Condition 2: M848- Other disorders of continuity of bone

Interventions

Intervention1: USG guided Interscalene Brachial plexus block: patients will receive an ultrasound guided interscalene brachial plexus block with 15ml of 0.5% Ropivacaine. Intervention2: USG guided Int

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 60 years of either sex ASA physical status I II patients with BMI 18-25 kg/m2 undergoing shoulder and proximal humerus surgeries under ultrasound guided interscalene brachial plexus block

Exclusion criteria

Exclusion criteria: 1. Patients allergic to local anaesthetics 2. Patients with infection at the injection site 3. Patients with coagulopathies or on anticoagulation medication. 4. Patients with pre-existing respiratory conditions 5. Patients with phrenic nerve or diaphragmatic dysfunction 6. Patients with neurological or neuromuscular disorders 7. Pregnancy and lactating women 8. Previous shoulder surgery on the same side 9. Patients with cervical spine pathology

Design outcomes

Primary

Measure	Time frame
To compare the diaphragmatic excursion and diaphragmatic thickness fraction between two groupTimepoint: evaluate preoperartively,30 minutes and 24 hours after intervention	—

Secondary

Measure	Time frame
To compare forced vital capacity between two groupsTimepoint: evaluate preoperartively,30 minutes and 24 hours after intervention;To compare pain scores between two groupsTimepoint: evaluate every 15 mins in first one hour and then every hour for 24 hours;To compare duration of sensory and motor block between two groupsTimepoint: nil;To compare adverse effects between two groupsTimepoint: evaluate every 15 mins in first one hour and then every hour for 24 hours	—

Measure

Time frame

To compare forced vital capacity between two groupsTimepoint: evaluate preoperartively,30 minutes and 24 hours after intervention;To compare pain scores between two groupsTimepoint: evaluate every 15 mins in first one hour and then every hour for 24 hours;To compare duration of sensory and motor block between two groupsTimepoint: nil;To compare adverse effects between two groupsTimepoint: evaluate every 15 mins in first one hour and then every hour for 24 hours

—

Countries

India

Contacts

Public ContactDrYVijayakumari

Government medical college,kadapa

vijayayedoti@gmail.com9963977191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026