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A Study Comparing Two Medicines (Norepinephrine and Phenylephrine) to Prevent Low Blood Pressure During Caesarean Delivery Under Spinal Anaesthesia.

A Randomised double blind study comparing prophylactic norepinephrine and phenylephrine boluses to prevent post-spinal anaesthesia hypotension in parturients scheduled for elective caesarean section under spinal anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112584
Enrollment
130
Registered
2026-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Intravenous Norepinephrine bolus immediately after SPINAL ANAESTHESIA: Hemodynamic parameters like heart rate, blood pressure, mean arterial pressure will be monitored at baseline,5,10

Sponsors

Government medical College Kadapa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA II Parturients betweeen 18-35 yrs of age with singleton , term gestation undergoing elective caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: parturient with coagulopathies, bleeding diathesis, known hypersensitivity to study drugs, with hypertensive disorders of pregnancy and preexisting hypertension and gestational diabetes mellitus, BMI greater than 35kg/m2 and fetal anomaly

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of prophylactic norepinephrine and phenylephrine bolus doses in preventing postspinal hypotension in women undergoing elective caesarean sectionTimepoint: Baseline,5 ,10,15,30,45,60 minutes after spinal anaesthesia—

Secondary

MeasureTime frame
To compare bradycardia, reactive hypertension, requirement of rescue boluses of vasopressors and or atropine , compare incidence of nausea and vomiting and neonatal outcomes between two groupsTimepoint: Baseline,5 ,10,15,30,45,60 minutes after spinal anaesthesia—

Countries

India

Contacts

Public ContactDr B Lakshmi Praveena

Government medical college,Kadapa

praveenadoc4all@gmail.com9494677801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026