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A study to evaluate the effectiveness of a nerve injection in patients with headaches caused by overuse of pain-relieving medicines

Effect of Greater Occipital Nerve Block on Headache Burden in Patients with Medication Overuse Headache: A Prospective Study (GON-MOH STUDY) - GON-MOH STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112571
Enrollment
30
Registered
2026-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G439- Migraine, unspecified

Interventions

Intervention1: The Greater Occipital Nerve Block(GON Block): Participants diagnosed with Medication Overuse Headache will receive bilateral Greater Occipital Nerve Blocks. Each block will consist of 2

Sponsors

AIIMS BHOPAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients with age more than 18 years of age. 2. Diagnosis of Medication Overuse Headache as per ICHD-3-beta. 3. Willingness to undergo nerve block and follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients with psychiatric disorders or those who are identified with psychiatric conditions during the course of the study will be excluded. 2. Secondary headache disorders 3. Coagulopathy or local infection at injection site 4. Pregnancy or lactation 5. History of Allergy to local anaesthetics or steroids 6. Prior occipital nerve block in last 6 months 7. Patients with history of any type of invasive procedure in occipital area 8. Patients with other disorders like malignancy, concomitant heart disease or severe comorbid pain.

Design outcomes

Primary

MeasureTime frame
Change in headache frequency (headache days per month)Timepoint: After 3 months of intervention which is greater occipital nerve block

Secondary

MeasureTime frame
Change in headache severity (VAS score) Change in headache-related disability (HIT-6) Change in acute medication intake Timepoint: After 3 months of intervention which is greater occipital nerve blocl

Countries

India

Contacts

Public ContactAGRATA SHARMA

AIIMS BHOPAL

dragrata@gmail.com09711453978

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026