Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than or equal to 18 years. 2. Histologically confirmed advanced or metastatic solid malignancy. 3. Receiving palliative care (without ongoing cancer-directed therapy, BSC) 4. Expected survival more than 4 weeks (clinician-estimated) 5. Able to undergo bedside POCUS assessment of the thigh 6.Provide informed consent (patient or legally authorized representative)
Exclusion criteria
Exclusion criteria: 1.Lower limb conditions affecting RF measurement: Thigh infection Large wounds Recent surgery or trauma Severe contractures 2. Significant lower limb oedema or anasarca 3. Known neuromuscular disorders affecting muscle bulk 4. Inability to position the patient supine for measurement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the association between baseline rectus femoris cross-sectional area and overall survival in advanced cancer patients receiving palliative care.Timepoint: Every 3 weeks for up to 6 months or until death. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess feasibility and reliability of RF-POCUS measurementsTimepoint: Every 3 weeks for up to 6 months or until death.;To compare RF measurements between cachectic and non-cachectic patients.Timepoint: Every 3 weeks for up to 6 months or until death.;To explore clinical factors influencing RF measurement and survivalTimepoint: Every 3 weeks for up to 6 months or until death. | — |
Countries
India
Contacts
Tata Memorial Hospital