A study to find out if injection of Botulinum Toxin A during thyroid surgery in study group participants,can improve the cosmetic appearance of scar in neck after surgery and comparing with the participants who don t receive the injection using questionnaires

Can Intraoperative injection of Botulinum Toxin A give a cosmetically superior scar following thyroidectomy? - A prospective Randomised control trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112494

Enrollment

100

Registered

2026-06-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E042- Nontoxic multinodular goiter Health Condition 2: E050- Thyrotoxicosis with diffuse goiter Health Condition 3: E065- Other chronic thyroiditis Health Condition 4: E041- Nontoxic single thyroid nodule Health Condition 5: E078- Other specified disorders of thyroid Health Condition 6: E052- Thyrotoxicosis with toxic multinodular goiter

Interventions

Intervention1: Intraoperative injection of Botulinum toxin A: Botulinum toxin A is injected into the platysma muscle during closure of thyroidectomy procedure and postoperatively scar is assessed for

Eligibility

Inclusion criteria

Inclusion criteria: All patients who undergo total thyroidectomy or hemithyroidectomy for various thyroid disorders above 18 years of age

Exclusion criteria

Exclusion criteria: 1.Patients with history of allergy to botulinum toxin 2. Patients with skin infections ,systemic fungal infections and neuromuscular disorders 3.Patients with uncontrolled diabetes 4.Patients who don t consent

Design outcomes

Primary

Measure	Time frame
Good cosmetic outcome and prevention of hypertrophic scar and keloid formationTimepoint: At discharge,after one month,after 3 months	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDrRNaveena MS

Madras Medical College

drsdhalapthy@gmail.com9790719570

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026