A study comparing two medicines (dexmedetomidine and dexamethasone) added to local anaesthesia in ultrasound-guided axillary brachial plexus block for forearm surgery to evaluate pain relief and duration of pain relief in patients with forearm fractures.

A randomized double blind study comparing efficacy of dexmedetomidine and dexamethasone as adjuvants to ropivacaine in ultrasound guided axillary brachial plexus block in patients posted for open reduction and internal fixation of fracture of both bones of the forearm - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/06/112482

Enrollment

Registered

2026-06-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M849- Disorder of continuity of bone, unspecified Health Condition 2: S529- Unspecified fracture of forearm

Interventions

Intervention1: Axillary brachial plexus block with Ropivacaine and Dexmedetomidine: To compare the duration of analgesia,onset and duration of sensory and motor block,hemodynamic variables,total rescu

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients between18 60years of age of either sex. 2.Patients belonging to American society of Anaesthesiologists (ASA) I and II, undergoing elective open reduction and internal fixation of fracture both bones forearm.

Exclusion criteria

Exclusion criteria: 1. Patients allergic to study drugs 2. Patients with neurological deficits 3. Patients on medication for chronic pain 4. Patients on anticoagulation therapy 5. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
To compare the duration of analgesia between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours	—

Secondary

Measure	Time frame
To compare the onset and duration of sensory and motor block between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare hemodynamic variables between the two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare total rescue analgesic consumption in 24 hours between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare adverse effects between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours	—

Measure

Time frame

To compare the onset and duration of sensory and motor block between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare hemodynamic variables between the two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare total rescue analgesic consumption in 24 hours between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours;To compare adverse effects between two groupsTimepoint: every 15 minutes for first one hour followed by every hourly for 24 hours

—

Countries

India

Contacts

Public ContactDR N Jagadeesh babu

Government medical college,kadapa

drjagadeeshnagella@gmail.com9949706327

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026