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A Split-Mouth Study Comparing Gel Foam Diclofenac and Gel Foam Ketorolac for Reducing Inflammation and Pain after Bilateral Tooth Extractions

Assessment of C-reactive protein level and clinical efficacy of gel foam diclofenac and gel foam ketorolac in bilateral symmetrical extractions: A split-mouth comparative study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/06/112475
Enrollment
26
Registered
2026-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K02- Dental caries

Interventions

Intervention1: DICLOFENAC: Absorbable gelatin sponge soaked with diclofenac sodium solution 50 mg/mL (or pre-formulated equivalent), applied to extraction socket, gently compressed and hled in place f
gel foam absorbs naturally over postoperative period (assessments at day 2 and 5, sutures removed at day 5). And total procedure -approximately 50 minutes (starting from the extraction procedure to su
gel foam absorbs naturally over postoperative period (assessments at day 2 and 5, sutures removed at day 5). And total procedure -approximately 50 minutes (starting from the extraction procedure to su

Sponsors

Asma Jamal Lari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 Patients Between 16-60 Years Of Age Patients With Bilateral Maxillary Or Mandibular Symmterical Extractions Site

Exclusion criteria

Exclusion criteria: Patients With Known Allergy To Nsaid Impacted Third Molar Lactating And Pregnant Women Patients On Any Other Analgesics Or Corticosteroids Patients With History Of Systemic Diseases Patients Not Giving Consent P

Design outcomes

Primary

MeasureTime frame
Primary outcome - TO EVALUATE Serum CRP levels in Diclofenac Gel foam group to evaluate serum CRP levels in ketorolac gel foam group . Timepoint: Primary outcome - Serum CRP levels (baseline, day 2, day 5)

Secondary

MeasureTime frame
Pain score (Visual Analog Scale - VAS) Facial swelling (linear measurements using flexible ruler) Wound healing (Landry et al. scale) Timepoint: Day 2 post-extraction, Day 5 post-extraction

Countries

India

Contacts

Public ContactDr Jagadish Chandra

Yenepoya Dental College

jagadishmds@rediffmail.com9845150871

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026